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Filtered Search Results
Medchemexpress LLC ER-27319 (maleate) | 1204480-26-1 | 99.4% | 396.44 | 50 MG
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ER-27319 (maleate), an acridone derivative, is a potent and selective SYK inhibitor. It inhibits the tyrosine phosphorylation of SYK and its activity, and can be used for study in allergic diseases. It also inhibits the release of antigen-induced allergic mediators from human and rat mast cells with an IC50 of 10 μM.
- Potent and selective SYK inhibitor
- Inhibits tyrosine phosphorylation of SYK
- Inhibits release of antigen-induced allergic mediators
- Suitable for study in allergic diseases
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Medchemexpress LLC Cediranib maleate | 857036-77-2 | 99.95% | 10 MM * 1 ML
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Cediranib maleate (AZD-2171 maleate) is a highly potent, orally available VEGFR inhibitor. It effectively inhibits Flt1, KDR, Flt4, PDGFRα, PDGFRβ, and c-Kit, making it a valuable tool for angiogenesis and cancer research.
- Potent inhibition of VEGF-stimulated proliferation and KDR phosphorylation in human umbilical vein endothelial cells.
- Reduces vessel area, length, and branching in in vitro vessel sprouting models.
- Ablates experimental angiogenesis and inhibits endochondral ossification in vivo.
- Inhibits growth of various human tumor xenografts in athymic mice.
- Induces microvessel density reduction and vascular regression in tumors.
- Actively investigated in clinical trials for various cancer types.
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Medchemexpress LLC Lisuride maleate | 19875-60-6 | 99.8% | 454.52 | 1 MG
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Lisuride is a potent dopamine agonist, acting directly on dopaminergic receptors. It is an ergot derivative that has been shown to alleviate premenstrual mastalgia. It is intended for research use only.
- Potent agonist of dopamine with a direct action on dopaminergic receptors
- Ergot derivative
- Releases premenstrual mastalgia without significant side effects
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Medchemexpress LLC Immh-010 maleate | 2541982-47-0 | 99.8% | 756.04 | 5 MG
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IMMH-010 maleate is a prodrug that acts as a novel PD-L1 inhibitor, showing potential antitumor activity. It is being investigated for the treatment of neurological disorders and advanced malignant solid tumors. Upon oral administration, it quickly converts into its active form, YPD-29B. This compound is significant for advancing research in the field of PD-L1 inhibitors and related therapeutic applications.
- Acts as a novel PD-L1 inhibitor
- Shows potential antitumor activity
- Investigated for neurological disorders and advanced malignant solid tumors
- Converts into active form, YPD-29B, upon oral administration
- Advances research in PD-L1 inhibitors and related therapeutic applications
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Medchemexpress LLC Enalapril maleate (Standard) | 76095-16-4 | 99.95% | 50 MG
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Enalapril maleate (Standard) is an analytical standard and an angiotensin-converting enzyme (ACE) inhibitor. This product is intended for research and analytical applications, commonly used in qualitative, quantitative, and methodological experiments such as HPLC, GC, and MS.
- Analytical standard for research and analytical applications
- Angiotensin-converting enzyme (ACE) inhibitor
- Suitable for HPLC, GC, and MS research experiments
- Molecular weight: 492.52
- Formula: C₂₄H₃₂N₂O₉
- Appearance: solid
- Color: white to off-white
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Medchemexpress LLC Enalapril maleate (standard) | 76095-16-4 | 99.95% | 100 MG
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Enalapril maleate (Standard) is an analytical standard of Enalapril maleate intended for research and analytical applications. This product, also known as MK-421 maleate, is the active metabolite of enalapril and acts as an angiotensin-converting enzyme (ACE) inhibitor. It is a reference standard for assaying and is commonly utilized in qualitative, quantitative, and methodological research experiments using techniques such as HPLC, GC, and MS.
- Serves as an analytical standard
- Suitable for research and analytical applications
- Functions as an angiotensin-converting enzyme (ACE) inhibitor
- Used in qualitative, quantitative, and methodological research experiments
- Compatible with HPLC, GC, and MS techniques
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Medchemexpress LLC Enalapril maleate (Standard) | 76095-16-4 | 100.0% | 25 MG
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Enalapril maleate (Standard) is an analytical standard and an angiotensin-converting enzyme (ACE) inhibitor. This product is intended for research and analytical applications, serving as a reference standard for assays.
- Reference standard for assay
- Used in qualitative, quantitative, and methodological research
- Applicable for HPLC, GC, and MS applications
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TARGETMOL CHEMICALS INC Ciproxifan maleate 10MG
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Also available in 1 mL, 1 mg, 2 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Ciproxifan maleate (FUB 359)(FUB-359 maleate) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes. Purity 99.45%
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Medchemexpress LLC 1-Octadecyl (2Z)-2-butenedioate | 2424-62-6 | MFCD08274815 | ≥98.0% | 368.55 g/mol | C22H40O4 | 500 MG
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Monostearyl maleate (1-Octadecyl (2Z)-2-butenedioate) is a long-chain alkyl ester used as a specialty reagent and intermediate in chemical synthesis and formulation research. It is supplied as a white to off-white solid and characterized for analytical and preparative work.
- High purity: ≥98.0%.
- Molecular formula: C22H40O4.
- Molecular weight: 368.55 g/mol.
- Appearance: white to off-white solid.
- Storage: store at room temperature; in solvent, -80°C (2 years) or -20°C (1 year).
- Analytical data: 1H NMR consistent with structure.
- Typical uses: ester intermediate and formulation reagent for research applications.
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Apexbio Technology LLC (+)-MK 801 Maleate 77086-22-7 10mM (in 1mL DMSO)
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( )-MK 801 Maleate is a non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor exhibiting a Ki value of approximately 30 5 nM By blocking the NMDA receptor-mediated ion channel MK 801 disrupts glutamate-associated excitatory neurotransmission In experimental models MK 801 demonstrates anticonvulsant and anxiolytic properties through modulation of NMDA receptor activity This compound readily penetrates the central nervous system binding reversibly and region-specifically to cortical and hippocampal membranes MK 801 effectively inhibits NMDA-triggered depolarization responses in neuronal preparations making it applicable in studies focused on epilepsy excitotoxicity and neuronal signaling pathways
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Cayman Chemical MK801 hydrogen maleate
Potent, selective and non-competitive NMDA receptor antagonist (Ki = 30.5 nM); acts at the NMDA receptor-operated ion channel as an open channel blocker, preventing Ca2+ flux
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eMolecules Benzyl tiglate stabilized with 0.1% alpha-tocopherol | 37526-88-8 | MFCD00017279 | 1g
Oakwood Chemical | Benzyl tiglate stabilized with 0.1% alpha-tocopherol | 1g | 537710580 | 104012 | | 37526-88-8 | MFCD00017279 | 190.242 | C12H14O2
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Medchemexpress LLC Cipralisant maleate | 223420-20-0 | 99.8% | 332.39 | C18H24N2O4 | 1 MG
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Cipralisant maleate is a research-grade histamine H3 receptor ligand used in pharmacology and neuroscience research. It acts as a potent, selective H3 receptor antagonist in vivo and may display agonist activity in certain in vitro assays. The material is supplied as a high-purity solid and is intended for experimental use under appropriate laboratory conditions.
- Potent, selective histamine H3 receptor ligand.
- Suitable for in vitro and in vivo pharmacology studies.
- High reported purity (≈99.8%).
- Stable as a powder when stored under recommended cold conditions.
- Available in small package sizes for research, including 1 mg.
- White to off-white solid appearance.
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Medchemexpress LLC Neratinib (maleate) | 915942-22-2 | MFCD30607264 | 99.7% | 673.11 | C34H33ClN6O7 | 10 MG
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Neratinib maleate is the maleate salt of neratinib, an orally available, irreversible inhibitor selective for HER2 and EGFR kinases. Supplied for research use, it is used to probe HER2/EGFR signaling and to evaluate kinase inhibition in preclinical studies.
- Irreversible HER2 and EGFR inhibitor with IC50s of 59 nM (HER2) and 92 nM (EGFR).
- High purity (99.7%) suitable for analytical and biological assays.
- Molecular weight 673.11 and formula C34H33ClN6O7.
- Stable as a solid at 4°C; in solution: -80°C (6 months) or -20°C (1 month), protect from light.
- Available in small milligram pack sizes for research applications.
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Apexbio Technology LLC Rosiglitazone maleate(Synonyms: Avandia, BRL 49653, BRL49653C, Rosiglitazone maleate salt, BRL49653, RGZ, Rosiglizole maleate), 25mg, CAS: 155141-29-0.
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Rosiglitazone maleate (CAS 155141-29-0) is the maleate salt formulation of rosiglitazone a thiazolidinedione compound targeting the nuclear receptor peroxisome proliferator-activated receptor gamma (PPAR ) By selective activation of PPAR rosiglitazone increases insulin sensitivity of peripheral tissues facilitating glucose uptake and reduction of blood glucose levels Due to its insulin-sensitizing activity rosiglitazone maleate serves as an important research tool in diabetes and metabolic syndrome investigations However recent clinical studies also report associations with adverse cardiovascular events fluid retention and anemia underscoring considerations for risk-benefit evaluation in ongoing research
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